The Pre-Vascularization of a Collagen-Chondroitin Sulphate Scaffold Using Human Amniotic Fluid-Derived Stem Cells to Enhance and Stabilize Endothelial Cell-Mediated Vessel Formation The authors investigated whether an amniotic fluid-derived stem cell-human umbilical vein endothelial cell co-culture could be used to engineer in vitro vasculature in a collagen chondroitin sulphate scaffold. [Acta Biomater] Abstract Molecular and Cellular Characteristics of Human and Non-Human Primate Multipotent Stromal Cells from the Amnion and Bone Marrow during Long Term Culture Human and non-human primate multipotent stromal cells (MSCs) were characterized for expression of MSC markers and capability of differentiation into mesenchymal lineages. The authors found that human and common marmoset samples shared many similar features such as most MSC markers and reduced major histocompatibility complex class I expression in amnion cells vs. bone marrow. [Stem Cell Res Ther] Full Article Optimal Route for Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation to Protect against Neonatal Hyperoxic Lung Injury: Gene Expression Profiles and Histopathology Scientists determined the optimal route of mesenchymal stem cell (MSC) transplantation. Gene expression profiling was performed to compare the effects of intratracheal versus intravenous MSC administration. [PLoS One] Full Article Amniotic Fluid Derived Stem Cells with a Renal Progenitor Phenotype Inhibit Interstitial Fibrosis in Renal Ischemia and Reperfusion Injury in Rats Investigators evaluated if mesenchymal stem cells derived from human amniotic fluid with a renal progenitor phenotype demonstrated a nephroprotective effect in acute ischemia reperfusion model and prevented late stage fibrosis. [PLoS One] Full Article Endothelial Progenitor Cells, Defined by the Simultaneous Surface Expression of VEGFR2 and CD133, Are Not Detectable in Healthy Peripheral and Cord Blood Scientists carried out an in depth investigation of circulating endothelial cell and their progenitor phenotypes in healthy peripheral blood, cord blood and bone marrow samples, by optimizing a reliable polychromatic flow cytometry panel. [Cytometry A] Abstract Hematopoietic Stem Cell Transplantation for CD40 Ligand Deficiency: Single Institution Experience Researchers conducted a retrospective analysis of seven patients who have undergone allogeneic hematopoietic stem cell transplantation (HSCT) for hyper-IgM syndrome syndrome. Allogeneic HSCT resulted in excellent survival and sustained immune reconstitution in patients with CD40 ligand deficiency using both myeloablative and reduced intensity conditioning approaches and various graft sources, including bone marrow, peripheral blood, and umbilical cord blood. [Pediatr Blood Cancer] Abstract |