| Press Release Mouse B-Type Lamins Are Required for Proper Organogenesis but Not by Embryonic Stem Cells
Investigators found that mouse embryonic stem cells do not need any lamins for self-renewal and pluripotency. [Science] Abstract | Press Release
Donor Cell Type Can Influence the Epigenome and Differentiation Potential of Human Induced Pluripotent Stem Cells
Investigators compared bona fide human induced pluripotent stem cells derived from umbilical cord blood cells and neonatal keratinocytes. [Nat Biotechnol] Abstract
Using iPSC-Derived Neurons to Uncover Cellular Phenotypes Associated with Timothy Syndrome
Researchers generated cortical neuronal precursor cells and neurons from induced pluripotent stem cells (iPSCs) derived from individuals with Timothy syndrome. [Nat Med] Abstract | Press Release
The Quantitative Proteomes of Human-Induced Pluripotent Stem Cells and Embryonic Stem Cells
Here, scientists present an in-depth quantitative mass spectrometry-based analysis of human embryonic stem cells, two different human-induced pluripotent stem cells and their precursor fibroblast cell lines. [Mol Syst Biol] Abstract
Regulated Expression and Role of c-Myb in the Cardiovascular-Directed Differentiation of Mouse Embryonic Stem Cells
The objective of this study is to define the role of c-Myb in smooth muscle cell differentiation from embryonic stem cells. [Circ Res] Abstract
The Differentiation and Isolation of Mouse Embryonic Stem Cells Toward Hepatocytes Using Galactose-Carrying Substrata
In this study, researchers report the effect of a matrix-dependent enrichment of embryonic stem cell-derived hepatocytes using immobilized poly(N-p-vinylbenzyl-4-O-β-d-galactopyranosyl-d-gluconamide) with E-cadherin-IgG Fc as a galactose-carrying substratum. [Biomaterials] Abstract
Generation of Mouse ES Cell Lines Engineered for the Forced Induction of Transcription Factors
Here investigators report the generation and characterization of 84 mouse embryonic stem cell lines with doxycycline-controllable transcription factors (TFs) which, together with the previous 53 lines, cover 7–10% of all TFs encoded in the mouse genome. [Sci Rep] Abstract