Delivery of Chemo-Sensitizing siRNAs to HER2+-Breast Cancer Cells Using RNA Aptamers Scientists describe a novel cell-based selection methodology that enables the identification of cell-internalizing RNA aptamers for targeting therapeutic small interfering RNAs (siRNAs) to human epidermal growth factor receptor 2 (HER2)-expressing breast cancer cells. [Nucleic Acids Res] Abstract
Peptide Vaccine Stimulates Immune Response in Patients with Breast Cancer According to 24-month results, patients with breast cancer assigned to the HER2-based peptide vaccine AE37 had immunologic responses compared with a control group. [Press release from the American Association for Cancer Research (AACR) discussing research presented at the AACR Annual Meeting 2012, Chicago] Press Release
Older Patients with Certain Breast Cancer Subtype May Not Benefit from Radiation Therapy New research suggests local breast radiation therapy may not be necessary for women with the luminal A subtype of breast cancer, particularly those aged older than 60. [Press release from the American Association for Cancer Research (AACR) discussing research presented at the AACR Annual Meeting 2012, Chicago] Press Release
Long-Term Use of Estrogen Hormone Therapy Linked to Higher Risk for Breast Cancer Researchers have linked the long-term use of estrogen plus progesterone and estrogen-only hormone therapy with a higher risk for developing breast cancer. [Press release from the American Association for Cancer Research (AACR) discussing research presented at the AACR Annual Meeting 2012, Chicago] Press Release
Link Between Inflammation and Breast Cancer Metastases Identified, May Be Treatable The incidence of breast cancer-associated metastasis was increased in animal models of the chronic inflammatory condition arthritis, according to preclinical results. [Press release from the American Association for Cancer Research (AACR) discussing research presented at the AACR Annual Meeting 2012, Chicago] Press Release
INDUSTRY NEWS
Canada and Japan Establish New Research Partnership The Canadian Institutes of Health Research and the Japan Science and Technology Agency recently signed a partnership agreement to fund joint research projects on the epigenetics of stem cells. [Canadian Institutes of Health Research] Press Release
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