SCIENCE NEWS Stem Cells from Fat May Help Heal Bone in Wounded Soldiers UC Davis biomedical engineer Kent Leach has received a CDMRP Hypothesis Development Award from the U.S. Army to explore a new approach to tissue regeneration that may speed bone healing and return to function. Dr. Leach will use stem cells derived from human adipose tissue to stimulate the formation of microvascular networks within developing bone. [PhysOrg Press Release]
|
|
CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Hypoxia Preconditioned Mesenchymal Stem Cells Improve Vascular and Skeletal Muscle Fiber Regeneration After Ischemia Through a Wnt4-dependent Pathway Researchers investigated the ability of mesenchymal stem cells, exposed to short-term hypoxic conditions, to participate in vascular and tissue regeneration in an in vivo model of hindlimb ischemia. [Mol Ther] A Differentiation-Based MicroRNA Signature Identifies Leiomyosarcoma as a Mesenchymal Stem Cell-Related Malignancy Here, researchers demonstrated that microRNAs are required for full smooth muscle cell differentiation of bone marrow-derived human mesenchymal stem cells. [Am J Pathol] Mesenchymal Stem Cells, Used As Bait, Disclose Tissue Binding Sites. A Tool in the Search for the Niche? Researchers developed an ex vivo approach characterizing renal mesenchymal stem cell adhesion to kidney sections. [Am J Pathol] Allogeneic Human Mesenchymal Stem Cells Restore Epithelial Protein Permeability in Cultured Human Alveolar Type II Cells by Secretion of Angiopoietin-1 Here, researchers tested the ability of human allogeneic mesenchymal stem cells to restore epithelial permeability to protein across primary cultures of polarized human alveolar epithelial type II cells following an inflammatory insult. [J Biol Chem] Isolation of Adipose-Derived Stem Cells and Their Induction to a Chondrogenic Phenotype Adipose-derived stem cells (ASCs) provide an abundant and easily accessible source of adult stem cells for use in regenerative approaches. This protocol first describes the isolation of ASCs from liposuction aspirate. [Nat Protoc] Effects of the Architecture of Tissue Engineering Scaffolds on Cell Seeding and Culturing Researchers assessed the influence of scaffold pore architecture on immortalised mesenchymal stem cell seeding and static culturing, by comparing a computer-designed gyroid architecture fabricated by stereolithography to a random-pore architecture resulting from salt-leaching. [Acta Biomater] LIGHT (TNFSF14) Inhibits Adipose Differentiation Without Affecting Adipocyte Metabolism LIGHT, a member of the tumor necrosis factor family, is a novel inhibitor of human adipocyte differentiation without adversely influencing central metabolic pathways in adipocytes. [Int J Obes] Function Analysis of Mesenchymal Bcor in Tooth Development by Using RNA Interference In this study, the Bcor expression pattern has been intensively investigated during mouse molar development. [Cell Tissue Res]
|
|
POLICY NEWS Hospital Clinic de Barcelona Obtained the First Accreditation for Cell Therapy Research The certification, awarded for the first time in Catalonia, allows the Hospital Clinic de Barcelona to produce drugs in gene therapy, cell therapy and tissue engineering. [Spanish Medicines Agency, Spain] New Videos Reveal How NIH Identifies the Most Promising Research Applications The National Institutes of Health’s Center for Scientific Review released a new video to show new applicants and others how NIH assesses over 80,000 grant applications each year to help find those with the most merit. [National Institutes of Health, United States] Publication of New Enforcement Strategy A new enforcement strategy has been published by the Inspection, Enforcement and Standards Division. [Medicines and Healthcare Products Regulatory Agency, United Kingdom] Drugs Designated as Orphan Drugs [Therapeutic Goods Administration, Australia] Therapeutic Goods Committee (TGC) (Updated) [Therapeutic Goods Administration, Australia]
|
|
EVENTS Worldwide Innovative Networking (WIN) Symposium in Personalized Cancer Medicine July 7-9, 2010 Paris, France Translational Cancer Medicine 2010 – USA July 11-14, 2010 San Francisco, United State 2nd International Conference on Cellular and Molecular Bioengineering (ICCMB2) August 2-4, 2010 Singapore City, Singapore Select Biosciences 3rd Annual Stem Cells Europe Conference August 24-25, 2010 Edinburgh, Scotland Select Biosciences Inaugural Cellular Therapy Summit August 24-25, 2010 Edinburgh, Scotland United Kingdom National Stem Cell Network (UKNSCN) 3rd Annual Scientific Conference July 12-14, 2010 Nottingham, United Kingdom Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Asia Pacific 2010 September 15-17, 2010 Sydney, Australia 5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010 October 5-7, 2010 Hannover, Germany 2010 American Society for Matrix Biology (ASMB) Meeting October 24-27, 2010 Charleston, United States 52nd American Society of Hematology (ASH) Annual Meeting and Exposition December 4-7, 2010 Orlando, United States Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference December 5-8, 2010 Orlando, United States Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community. JOB OPPORTUNITIES Senior Scientist – Magnetic Cell Separation (STEMCELL Technologies) Business Development Manager Europe – Cell Therapy Products (Pall Corporation) Manager/Sr. Manager, Therapeutic Cell Solutions, Process Development (Lonza) Reach more than 11,000 potential candidates by posting your organization’s career opportunities with Mesenchymal Cell News. Visit here to post your career opportunities.
Have we missed an important article or publication in Mesenchymal Cell News? Click here to submit! Comments or Suggestions? Email info@connexoncreative.com with your feedback. |
|
|