Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Pulmonary Infection Caused by Pseudomonas aeruginosa via Inhibiting Overproduction of Prostaglandin E2 The therapeutic and mechanistic effects of adipose tissue-derived mesenchymal stem cells on P. aeruginosa pulmonary infection were evaluated in a murine model of P. aeruginosa pneumonia. [Stem Cells] Abstract Natural Assembly of Platelet Lysate-Loaded Nanocarriers into Enriched 3D Hydrogels for Cartilage Regeneration In vitro release studies were carried out focusing on the quantification of PDGF-BB and TGF-β1 growth factors. Human adipose derived stem cells were entrapped in 3D hydrogels and cultured in vitro under chondrogenic stimulus, in order to assess their potential use for cartilage regeneration. [Acta Biomater] Abstract Differentiation Potential of Human Chorion-Derived Mesenchymal Stem Cells into Motor Neuron-Like Cells in Two- and Three-Dimensional Culture Systems Since there is no report on potential of human chorion-derived mesenchymal stem cells (C-MSCs) to differentiate into motor neuron cells in two- and three-dimensional culture systems, scientists set out to determine the effect of retinoic acid and sonic hedgehog on differentiation of human C-MSCs into motor neuron-like cells cultured on tissue culture plates and electrospun nanofibrous gelatin scaffold. [Mol Neurobiol] Abstract Extracellular Vesicles Secreted by Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stromal Cells Fail to Suppress Lymphocyte Proliferation Researchers compared the immunosuppressive potency of mesenchymal stromal cells derived from bone marrow and adipose tissue, with their secreted extracellular vesicles in a standardized lymphocyte proliferation assay. [Stem Cells Dev] Abstract Three-Dimensional Differentiation of Adipose-Derived Mesenchymal Stem Cells into Insulin-Producing Cells Researchers evaluated the collagen/hyaluronic acid scaffold effect on the differentiation of insulin-producing cells from adipose-derived mesenchymal stem cells. Adipose-derived mesenchymal stem cells were cultured and seeded in a collagen/hyaluronic acid scaffold and then treated with induction media. [Cell Tissue Res] Abstract Intravenous Delivery of Adipose-Derived Mesenchymal Stromal Cells Attenuates Acute Radiation-Induced Lung Injury in Rats Researchers evaluated the therapeutic capacity of adipose-derived mesenchymal stromal cells (Ad-MSCs) to heal acute radiation-induced lung injury (RILI) in rats. Intravenous delivery of Ad-MSCs attenuated acute RILI. [Cytotherapy] Abstract Tonsil-Derived Mesenchymal Stromal Cells Produce CXCR2-Binding Chemokines and Acquire Follicular Dendritic Cell-Like Phenotypes under TLR3 Stimulation Scientists analyzed the expression profile of Toll-like receptors (TLRs) in mesenchymal stromal cells from human tonsils (T-MSCs) and stimulated the T-MSCs with TLR agonists. TLR3 stimuli induced C-C chemokine receptor type 6 expression in T-MSCs after 24 hours. [Cytokine] Abstract Buyang Huanwu Decoction (BYHWD) Enhances Angiogenic Effect of Mesenchymal Stem Cell by Upregulating VEGF Expression after Focal Cerebral Ischemia Researchers aimed to clarify the mechanism of BYHWD on angiogenesis mediated by mesenchymal stem cells (MSCs). Exosomes from MSCs and MSCs treated by BYHWD induced elevated microRNA (miRNA)-126 expression and reduced miR-221 and miR-222 expression. [J Mol Neurosci] Abstract |