| PUBLICATIONS (Ranked by Impact Factor of the Journal) | LABORATORY RESEARCH Polo-Like Kinase 1 Facilitates Loss of Pten-Induced Prostate Cancer Formation In this study, researchers demonstrate that Pten-depleted cells suffer from mitotic stress, and that nuclear function of Pten, but not its phosphastase activity, is required to reverse this stress phenotype. [J Biol Chem] Abstract The ß-Catenin Binding Protein ICAT Modulates Androgen Receptor Activity Researchers investigated inhibitor of ß-catenin and T-cell factor (ICAT), a ß-catenin binding protein that inhibits the canonical Wnt/ß-catenin signaling pathway, in androgen receptor signaling. [Mol Endocrinol] Abstract Neonatal Exposure to High Doses of 17ß-Estradiol Results in Inhibition of Heparanase-1 Expression in the Adult Prostate Researchers investigated the expression of heparanase-1 in the ventral prostate of 90-day-old rats after neonatal exposure to a high dose of 17ß-estradiol. [Histochem Cell Biol] Abstract Contractions of the Mouse Prostate Elicited by Acetylcholine Are Mediated by M3 Muscarinic Receptors This study investigates the muscarinic receptor subtype responsible for the cholinergic contractile response in the mouse prostate gland. [J Pharmacol Exp Ther] Abstract Vitamin D3 Cryosensitization Increases Prostate Cancer Susceptibility to Cryoablation via Mitochondrial-Mediated Apoptosis and Necrosis This study describes a molecular basis of Vitamin D3 cryosensitization including the response and efficacy of the combination in both androgen-sensitive and insensitive prostate cancer. [BJU Int] Abstract Focal Laser Interstitial Thermotherapy (LITT) at 980nm for Prostate Cancer: Treatment Feasibility in Dunning R3327-AT2 Rat Prostate Tumor The objective of this study was to examine the feasibility and reproducibility of LITT as a minimally invasive method for the treatment of prostate cancer. [BJU Int] Abstract CLINICAL RESEARCH Phase III Trial of Selenium to Prevent Prostate Cancer in Men with High-Grade Prostatic Intraepithelial Neoplasia: South West Oncology Group S9917 In vitro, in vivo, epidemiologic, and clinical trial evidence that selenium supplementation protects against prostate cancer motivated this double-blind, randomized, placebo-controlled trial of selenium 200 (µg/d) as selenomethionine in men with high-grade prostatic intraepithelial neoplasia. [Cancer Prev Res] Abstract Increased Expression of Putative Cancer Stem Cell Markers in Primary Prostate Cancer is Associated with Progression of Bone Metastases This current study aimed to test the hypothesis that the development of bone metastasis correlates with the proportion of prostate cancer stem cell-like cells present in the primary tumor. [Prostate] Abstract Underestimation of Gleason Score at Prostate Biopsy Reflects Sampling Error in Lower Volume Tumors The objective of this study was to determine the influence of tumor and prostate gland volumes on the underestimation of prostate cancer Gleason score in diagnostic core biopsies. [BJU Int] Abstract Diffusion Tensor Imaging of Normal Prostate at 3T: Effect of Number of Diffusion-Encoding Directions on Quantization and Image Quality The purpose of this study was to prospectively investigate differences of diffusion tensor imaging using a different number of diffusion-encoding directions and to evaluate the feasibility of tractography in healthy prostate at 3T. [Br J Radiol] Abstract |
|
|
|