| Vol. 12.05 – 11 February, 2021 |
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| The effects of human plasma enriched in bone marrow stem cell soluble factors by granulocyte colony stimulating factor mobilization, umbilical cord blood plasma, and their activated forms on ovarian niche, follicle development and breeding performance were assessed in mouse models of chemotherapy-induced ovarian damage. [American Journal of Obstetrics and Gynecology] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists investigated whether the MSC-extracellular vesicles miRNA cargo had the capacity to modulate the exacerbated cytokines, cell death and coagulation disturbs present in severe COVID-19. [Stem Cell Reviews and Reports] |
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| The authors report that retinoid X receptor (RXR) activity was of significance for cord blood (CB) hematopoietic stem cells (HSC) ex vivo expansion. RXR antagonist HX531 significantly promoted ex vivo expansion of CB HSCs and progenitor cells. [Stem Cell Reviews and Reports] |
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| In this Phase I clinical trial, researchers present the safety, feasibility, and tolerability of the multiple infusions of high dose MSCs, which originated from the placenta and umbilical cord, in critically ill COVID-19-induced acute respiratory distress syndrome (ARDS) patients. [Stem Cell Research & Therapy] |
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| Scientists investigated the chondrogenic potential of amniotic fluid stem cells in a micromass system under insulin-like growth factor 1 stimuli, as well as to look at their potential to differentiate directly when cultured in a porous chitosan-xanthan scaffold. [Scientific Reports] |
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| Researchers optimized the culture conditions for umbilical cord‐MSCs by using a good manufacturing practice‐compatible serum‐free medium, developed in‐house, and a small‐scale bioreactor, which was later scaled up to 500 mL. [Biotechnology Journal] |
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| The authors investigated the effect of exosomes and miR-18b-3p/leptin (LEP) on occurrence of preeclampsia. The morphology of the human umbilical cord (hUC) MSCs and hucMSC-exosomes was identified. [Nanoscale Research Letters] |
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| First-trimester placental chorion mesenchymal stem cells (CMSCs) and third-trimester CMSCs were isolated and characterized, and then they were subjected to in vitro endothelial cell differentiation induction and tube formation to evaluate angiogenic ability. [Heliyon] |
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| Investigators overview the recent progress, challenges, and future perspectives in the use of amniotic membrane as a delivery platform for stem cells. [Life Sciences] |
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| AbbVie and Caribou Biosciences, Inc. announced that they have entered into a collaboration and license agreement for the research and development of chimeric antigen receptor (CAR)-T cell therapeutics. [Caribou Biosciences, Inc.] |
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| National University of Ireland Galway – Galway, Ireland |
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| University of Oxford – Oxford, England, United Kingdom |
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| St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| The Jackson Laboratory – Bar Harbor, Maine, United States |
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| Blood Research Institute – Milwaukee, Wisconsin, United States |
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