 | | Vol. 14.29 – 26 July, 2022 |
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| Researchers engineered programmed death ligand-1 and cytotoxic T lymphocyte antigen 4 immunoglobulin fusion protein–modified MSCs as accessory cells for islet cotransplantation.
[Science Advances] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists explored the function and mechanism of MSC-transformed cancer associated fibroblasts cells (MT-CAFs) on progression of colon cancer.
[Stem Cell Research & Therapy] |
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| Paramagnetic element-doped upconversion nanoparticles’ potential in cell labeling and in vivo tracking applications was comprehensively explored.
[Journal of Biomedical Materials Research Part A] |
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| Researchers evaluated the feasibility, cell viability, and stem cell marker stability of 3D-cultured equine bone marrow-derived MSCs and determined the effect of inflammatory stimulation upon gene expression and secretion of key regulators of inflammation.
[Stem Cells and Development] |
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| To address the question of determining the osteogenic differentiation of MSCs, bone marrow studies were performed using probe microscopy.
[Contrast Media & Molecular Imaging] |
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| The authors evaluated the impact of tissue maintenance under different conditions on MSCs derived from adipose tissue.
[BMC Veterinary Research] |
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| Scientists investigated the effects of the static magnetic field and electromagnetic field on reactive oxygen species (ROS) production and the acidic pH conditions as stimuli to change cell cycle progression and cell death in MSCs.
[Radiation Research] |
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| MSCs were grown under ambient conditions or a metabolic switching paradigm by alternating galactose and glucose in medium and then assayed for oxygen consumption rates using the Seahorse technology.
[Neuromolecular Medicine] |
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| Investigators revealed that PTEN or LKB1 deficiency in Gli1+ gut mesenchymal cells, but not intestinal epithelium, drove polyp formation histologically resembling polyposis in human patients.
[Cell Reports] |
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| MSCs may serve as a novel tool to investigate the full epigenome beyond DNA methylation, to explore other omics levels, and to perform functional assays.
[Trends in Endocrinology and Metabolism] |
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| Exosomes, as communicators, carry various RNAs and proteins and thus link MSCs and the tumor microenvironment, which provides options for improving outcomes and developing targeted treatment.
[Cell Death Discovery] |
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| Investigators review current findings regarding the immunomodulatory and regenerative mechanisms of MSCs, as well as their therapeutic applications in diabetes mellitus (DM) and DM-related complications.
[Cellular Reprogramming] |
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| QBiotics Group Limited has been granted approval of its Investigational New Drug application by the US FDA for lead oncology molecule, tigilanol tiglate.
[QBiotics Group Limited] |
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| November 7 – 8, 2022
London, England, United Kingdom |
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| | Sanford Research – Sioux Falls, South Dakota, United States |
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| | Lehigh University – Bethlehem, Pennsylvania, Untied States |
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| | Michigan Medicine – Ann Arbor, Michigan, United States |
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| | The Chinese University of Hong Kong – Hong Kong, China |
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| | UT Health Science Center at San Antonio – San Antonio, Texas, United States |
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