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[Oncogene] The authors used the azoxymethane/dextran sulfate sodium model to induce colorectal cancer and investigate the role of carbohydrate response element-binding proteinin colorectal carcinogenesis in vivo.

[British Journal of Cancer] Scientists investigated the hypothesis that Notch signaling, through RBP-J, directly transcriptionally regulates SMAD2 and SMAD3, thereby modulating transforming growth factor-beta (TGF-β) pathway output.

[Cell Death & Disease] Stable OTUB2 overexpression and knockdown cells were cocultured with M0 macrophages to study tumor-associated macrophages polarization.

[Nature] Investigators showed that metastasis-associated oncofetal cell states already emerge at the earliest stages of colorectal cancer, concurrent with invasive front formation.

[International Journal of Molecular Medicine] Scientists highlight the gastric cancer‑specific mechanisms, controversial scientific issues and latest clinical translation progress of RNA‑binding proteins (RBPs) and propose personalized treatment strategies based on the molecular characteristics of RBPs.

[Advanced Materials] A bottom-up biomaterial-based platform was introduced to program cell state changes in pancreatic cancer organoids by tuning minimal adhesion cues within a synthetic matrix.