Muscle Cell News

Muscle Cell News is an online resource dedicated to the latest research into smooth, skeletal, and cardiac muscle cells.

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Microfluidic Modeling of Macrophage-Induced Cardiac Inflammation Using NF-κB Reporter Cardiomyocytes

February 23, 2026

[Advanced Healthcare Materials] Researchers developed an in vitro cardiac inflammation model that enables controlled investigation of macrophage-cardiomyocyte interactions.

Empagliflozin Protects against Doxorubicin-Induced Arrhythmia by AMPK/mTOR-Mediated Autophagy in Cardiomyocyte

February 23, 2026

[European Journal of Pharmacology] Investigators demonstrated that empagliflozin reduced the incidence of ventricular arrhythmia by regulating AMPK/mTOR signaling and restored autophagic flux in DOX-treated rats and neonatal rat ventricular cardiomyocytes.

Distinct HIF1α and HIF2α Functions Control Skeletal Muscle Metabolism and Erythropoiesis

February 23, 2026

[Journal of Clinical Investigation] Scientists developed mice with myofiber-specific knockouts of prolyl hydroxylase proteins, in which HIFα is stabilized, and inducible myofiber-specific overexpression of stable HIF1α or HIF2α to explore the role of HIFα in myofibers.

Mouse Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene to Instruct Regeneration

February 23, 2026

[Elife] Using adult mouse skeletal muscles, the authors show that Scx expression is not detectable in adult muscle stem cells during quiescence.

A Novel Computational Model of Human iPSC-Derived Ventricular Myocytes with Improved L-Type Calcium Current for Application to Timothy Syndrome

February 23, 2026

[Scientific Reports] Researchers demonstrated a computational framework that offers a flexible and physiologically grounded tool for investigating the mechanisms of arrhythmogenesis in human-induced pluripotent stem cell-derived cardiomyocytes and for supporting personalized medicine applications.

Histone Methyltransferase G9a Drives Vascular Smooth Muscle Cell Proliferation and Intimal Hyperplasia in Mice

February 23, 2026

[Acta Pharmacologica Sinica] The authors investigated the role of G9a in promoting vascular smooth muscle cell proliferation and vascular intimal hyperplasia and the underlying mechanisms.

UAMC-3203 Attenuates Aortic Dissection by Targeting Ferroptosis-Mediated Vascular Smooth Muscle Cell Loss

February 23, 2026

[Life Sciences] Human aortic vascular smooth muscle cells were used to investigate UAMC-3203's mechanism.

Wnt11 Mediates Fibroblast-Smooth Muscle Cell Interaction to Promote Neurogenic Bladder Fibrosis in Rats

February 23, 2026

[Communications Biology] Scientists found that Wnt11 is significantly up-regulated in the rat fibrotic bladders induced by bilateral pelvic nerve injury and spinal cord injury, and promotes bladder fibroblasts-to-myofibroblasts transition and smooth muscle cells phenotypic transformation.

Therapeutic Strategies Targeting Muscle Stem Cells in Satellite Cell-Opathies

February 23, 2026

[Journal of Neuromuscular Diseases] The authors explore the pathophysiology of satellite cell-opathies, highlighting key molecular mechanisms underlying their dysfunction.

Solid Biosciences Announces Positive Feedback from Type C Meeting with FDA for SGT-003 Gene Therapy for Duchenne Muscular Dystrophy

February 23, 2026

[Solid Biosciences, Inc.] Solid Biosciences, Inc. announced a positive regulatory update from its recent Type C meeting with the US FDA that supports the continued advancement of SGT-003 as a potential treatment for Duchenne muscular dystrophy.

Salvia Miltiorrhiza-Derived Vesicle-Like Nanoparticles Functionalised Hydrogel with Excellent Ability of Oxidative Stress Modulation and Anti-Cardiomyocyte Apoptosis for Sepsis-Induced Myocardial Injury

February 10, 2026

[Plant Biotechnology Journal] Researchers introduced Salvia miltiorrhiza-derived nanoparticles (SDVLNs) to counteract ROS effects after myocardial infarction. They performed in vitro experiments to analyse the effects of SDVLNs on cardiomyocyte proliferation, migration, oxidative stress, and mitochondrial function.

Treadmill Exercise Activates Mechanosensitive Piezo1 to Inhibit Cardiomyocyte Apoptosis and Improve Cardiac Function after Myocardial Infarction in Mice

February 10, 2026

[Basic Research in Cardiology] Piezo1 knockdown impaired exercise-induced reductions in cardiomyocyte apoptosis, survival benefits, and attenuation of fibrosis.

Every day, our editorial team sifts through the most recent scientific literature to help keep researchers and medical professionals current. Muscle Cell News covers the three types of muscle cells: cardiac, skeletal, and smooth muscle. We cover a broad range of topics, including cell culturing, muscle regeneration, and musculoskeletal disorders.