 | | Vol. 15.28 – 15 August, 2024 |
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| Investigators reported the fragile X-related protein 1 (FXR1) network, an mRNA-protein network present throughout the cytoplasm, formed by FXR1-mediated packaging of exceptionally long mRNAs.
[Cell] |
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 | | PUBLICATIONSListed by the impact factor of the journal |
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| Researchers analyzed transcriptomic responses of human clinical isolates of S. aureus from initial and chronic infections. They observed upregulated collagenase and proline transporter gene expression in chronic infection isolates.
[Nature Microbiology] |
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| The authors observed that softer, lightly crosslinked hydrogels promoted greater cellular infiltration and resulted in smaller scars compared to stiffer, heavily crosslinked hydrogels.
[Nature Communications] |
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| A novel core-shell microneedle (CSMN) patch was designed for the sequential delivery of tannic acid-magnesium complexes and extracellular vesicles from Lactobacillus druckerii.
[Small] |
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| A tumor-targeting TME and electric field stimuli-responsive nanozyme was developed, which was capable of catalyzing the generation of ROS to induce cell death and releasing carbon monoxide (CO) specifically in tumor tissues for on-demand CO therapy and immunotherapy.
[Small] |
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| The authors showed that estrogen-related receptor gamma (ERRγ) was overexpressed in metastatic small-cell lung cancer (SCLC) tumors, and is positively associated with SCLC progression.
[EMBO Molecular Medicine] |
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| The authors found that Smac mimetic compounds (SMC) resistance was not due to a cell-intrinsic mechanism of resistance. They evaluated the contribution of glioblastoma and brain stromal components to identify parameters leading to SMC efficacy and resistance.
[Cell Death & Disease] |
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| Investigators developed a novel agarose-collagen composite microsphere implant for skin tissue regeneration. Fabricated using an emulsification-crosslinking method, these microspheres exhibited excellent uniformity and sphericity, as well as attractive injectability.
[International Journal of Biological Macromolecules] |
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| Cytokine secretion, macrophage adhesion and gene expression were measured by ELISA, confocal microscopy and RT-PCR. Cell adhesion and collagen secretion were evaluated in HGF cultures.
[Journal of Materials Chemistry B] |
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| Scientists investigated the expression and significance of insulin-like growth factor binding protein 5 and ECM related proteins in anterior vaginal wall tissues among aged pelvic organ prolapse patients.
[Scientific Reports] |
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| The authors examine the potential to extract value from the collagen content present in animal-derived waste and by-products. They provide a systematic evaluation of different species groups and discuss various approaches for processing and fabricating repurposed collagen.
[International Journal of Biological Macromolecules] |
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| Investigators review the application of Type II collagen in tissue engineering and highlight its crucial contributions to the regeneration of hyaline cartilage and intervertebral discs.
[Communications Materials] |
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| BSF Enterprise announced that Kerato has entered into a Heads of Terms agreement and research partnership with the University of Montreal in Canada to develop an in situ gelling cornea that offers a novel treatment for corneal damage and full thickness perforations.
[Med-Tech (BSF Enterprise)] |
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| Dr. Ajisafe Victor Ayobami, who pursued his PhD in Biomaterials and Tissue Engineering at the prestigious institute, emerged as a standout by developing innovative therapeutic biomaterials derived from snail mucus for the treatment of osteoarthritis.
[Platform Times] |
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| September 17 – 19, 2024
Geneva, Switzerland |
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| | Ludwig Boltzmann Institute for Traumatology – Vienna, Austria |
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| | University of Oulu – Oulu, Finland |
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| | Cancer Research UK – Bearsden, Scotland, United Kingdom |
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| | University of Oxford – Oxford, England, United Kingdom |
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| | Max Planck Institute – Planegg, Germany |
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