 | | Vol. 8.34 – 16 September, 2022 |
| |
|
|
| The authors demonstrated that transit-amplifying cells, marked by unconventional prefoldin RPB5 interactor, controlled R-spondin production to guide intestinal stem cell proliferation.
[Journal of Experimental Medicine] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Researchers revealed significant differences in coronin-like actin-binding protein 1C derived circRNA hsa_circ_0000437 between gastric cancer and para-cancer tissues.
[Oncogene] |
|
|
|
| Investigators screened several representative food-borne comparator engineered nanomaterials and reported that human colon cancer cells could insidiously exploit ZnO nanoparticle-induced adaptive response to acquire resistance against several chemotherapeutic drugs.
[Nanoscale] |
|
|
|
| Scientists identified a second adhesion complex localized at the proximal base region of microvilli. This complex contained the immunoglobulin superfamily member TMIGD1, which directly interacted with the microvillar scaffolding proteins EBP50 and E3KARP.
[Science Signaling] |
|
|
|
| CircRNA microarray and quantitative real time-polymerase chain reaction analyses were performed to investigate and verify the candidate dysregulated circRNA.
[Cell Death & Disease] |
|
|
|
| Functionally, circPGD promoted cell proliferation, migration, and suppressed apoptosis in vitro. Mechanistically, circPGD sponged miR-16-5p for relieving miR-16-5p suppression on the corresponding target ABL2 via the SMAD2/3 and YAP signaling pathways.
[Cell Death Discovery] |
|
|
|
| The authors provide evidence that the expression of cancer stem cell‑related genes and their potential regulatory miRNAs contribute to intra‑tumor heterogeneity in colorectal carcinoma, lymph node, and liver metastasis.
[Oncology Reports] |
|
|
|
| Scientists investigated the role of NudCD1 in spindle assembly checkpoint regulation and in the prognosis of colorectal cancer.
[BMC Cancer] |
|
|
|
| Since mTOR, Astrin, and hypoxia-inducible factors are involved in promoting the growth and survival of cancer cells, researchers investigated the possible interaction between them in cultured colon cancer cells.
[Biochemistry and Biophysics Reports] |
|
|
|
|
| The authors present an overview of the current understanding of the role of goblet cells and the mucus layer in maintaining intestinal health during steady-state and how alterations to these systems contribute to inflammatory and infectious disease.
[Nature Reviews Gastroenterology & Hepatology] |
|
|
|
| Investigators discuss the beneficial effects of metformin on IBD using the results of in vitro, in vivo, and clinical studies.
[International Immunopharmacology] |
|
|
|
|
| Agenus announced the initiation of a global Phase II program of botensilimab, an Fc-enhanced anti-CTLA-4 that activates innate and adaptive immune responses.
[Agenus] |
|
|
|
|
| February 19 – 22, 2023
Banff, Alberta, Canada |
|
|
|
|
|
| | Sunnybrook Research Institute – Toronto, Ontario, Canada |
|
|
|
| | Columbia University – New York, New York, United States |
|
|
|
| | STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
|
|
|
| | Technical University of Denmark – Lyngby, Denmark |
|
|
|
| | Beckman Research Institute of City of Hope – Duarte, California, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
