 | | Vol. 8.33 – 16 October, 2023 |
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| By dynamic cardiac function measurement, investigators discovered that the initiation of sudden hemodynamic collapse was on day four in the mouse model of fulminant myocarditis.
[Cell Discovery] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| In vivo fluctuations of both intra- and extracellular metabolite levels during ischemia-reperfusion were explored via microdialysis and tissue metabolome analysis.
[Circulation Research] |
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| By studying pathogenic deletion mutations in the desmosomal protein plakophilin-2 (PKP2), investigators identified a general mechanism by which PKP2 delocalization restrictED actomyosin network organization and cardiac sarcomeric contraction in ACM.
[Nature Communications] |
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| Scientists reported that transcription factor Ebf1 was highly expressed in non-myocytes and potently regulates heart development.
[Development] |
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| Researchers developed an engineering strategy to tune the therapeutic potential of extracellular vesicles using nanotopographical cues.
[ACS Nano] |
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| Scientists demonstrated that doxorubicin triggered severe muscle atrophy via upregulation of oxidative stress and atrogenes in association with decreased expression of the antioxidant enzyme extracellular superoxide dismutase, in cultured C2C12 myotubes and mouse skeletal muscle.
[Journal Of Physiology] |
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| C2C12 cells, an in vitro model of muscle cells, were differentiated for two or six days in the presence of hypocalcemia and moderate or severe hyperphosphatemia, or combinations of both conditions.
[Journal Of Endocrinological Investigation] |
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| Investigators determined the impact of human recombinant irisin on the growth and development of three-dimensional engineered skeletal muscle. Muscle satellite cells were cultured without irisin, or with either 50 ng/ml, 100 ng/ml, or 250 ng/ml of irisin supplementation.
[Tissue Engineering Part A] |
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| | Single-molecule spatial distribution of transcripts from 140 genes was analyzed in fresh-frozen human thoracic aortic aneurysm samples with region and sex-matched controls.
[Arteriosclerosis Thrombosis And Vascular Biology] |
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| Investigators demonstrated that cellular prion was expressed in the rat metrial gland, the entry point of spiral arteries with the highest expression on E16.5, the day at which trophoblast invasion peaked.
[Journal of Cellular Physiology] |
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| Researchers examined how inhibition of protein kinase C, rho-kinase, and integrin-link kinase affected force potentiation in sheep carotid artery.
[Journal Of Applied Phycology] |
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| Scientists provide a comprehensive update on nuclear mechanisms, their interactions, and their integration in controlling smooth muscle cell homeostasis and dysfunction.
[The American Journal of Pathology] |
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| The authors summarize the recent findings on the effect of hypoxia and hypoxia signaling on the key aspects of muscle physiology, namely, stem cell maintenance and myogenesis.
[Advanced Biology] |
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| Tulane epidemiologist and professor Dr. Jiang He has been elected to the National Academy of Medicine — one of the highest honors in the fields of health and medicine — for leading hypertension research that has helped transform cardiovascular disease prevention efforts across the globe.
[Tulane University] |
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| October 23 – 25, 2023
Toronto, Ontario, Canada |
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| | University College London – London, England, United Kingdom |
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| | The University of Tennessee – Memphis, Tennessee, United States |
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| | University of Houston – Houston, Texas, United States |
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| | Northwestern University – Chicago, Illinois, United States |
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