Noshin Noorjahan

[Scientific Reports] The authors reported an original, fully-human in vitro 3D model of the bone marrow microenvironment dedicated to study interactions taking place between mesenchymal stromal cells and hematopoietic stem and progenitor cells during the hematopoietic differentiation.

[Aging Cell] Scientists established cortical organoids derived from Hutchinson-Gilford progeria syndrome (HGPS) patient-iPSCs from patients with HGPS to investigate the role of progerin in the brain.

[Journal of Nanobiotechnology] The authors investigated the impact of maternal exposure to polypropylene nanoplastics on fetal brain development and neurobehavioral outcomes in a mouse model and further explored its mechanism in human cerebral organoids.

[UMass Chan Medical School] Megan Orzalli is one of eight recipients of the 2025 Investigators in the Pathogenesis of Infectious Disease award from the Burroughs Wellcome Fund.

[Science Signaling] Researchers tested the leucine-rich repeat kinase 2 (LRRK2) inhibitor MLi-2 in a mouse model of early stage, LRRK2 mutation–associated Parkinson's disease.

[Nature Communications] Scientists investigated the association between glial reactivity and synaptic dysfunction biomarkers in cerebrospinal fluid from 478 individuals in cognitively unimpaired and cognitively impaired individuals.