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Pulmonary Cell NewsAll Articles by Author:
Noshin Noorjahan
ESC & iPSC News
Induced Neural Progenitor Specification from Human Pluripotent Stem Cells by a Refined Synthetic Notch Platform
[ACS Synthetic Biology] Scientists presented a method for cell-guided differentiation using the synthetic Notch receptor platform to regulate sonic hedgehog production and subsequent cell fate specification.
ESC & iPSC News
KDM3A and KDM3B Regulate Alternative Splicing in Mouse Pluripotent Stem Cells
[iScience] Scientists uncovered a surprising role for the KDM3 proteins in post-transcriptional regulation of mESCs. Proteomic analysis shows KDM3A and KDM3B interacting with RNA processing factors such as EFTUD2 and PRMT5.
Muscle Cell News
FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes
[Circulation Research] Type 2 diabetes increased cardiac CD36 S-acylation, CD36 sarcolemmal localization, fatty acid oxidation rates, and triglyceride storage in the diabetic heart.
Muscle Cell News
SENP2-Mediated Desumoylation of NCOA4 Protects against Ferritinophagy-Dependent Ferroptosis in Myocardial Ischemia-Reperfusion Injury
[Autophagy] Researchers found that SENP2 expression decreased following myocardial ischemia reperfusion injury. Deletion of SENP2 increased cardiomyocyte ferroptosis and hindered cardiac function recovery after myocardial ischemia-reperfusion injury.
Newsletters
Endogenous Glucocorticoid Receptor Activation Modulates Early-Stage Cell Differentiation in Pancreatic Progenitors of Mice and Humans
[Development] The authors investigated glucocorticoid receptor signaling during early pancreas development in mice and humans.
Newsletters
Glucagon-Like Peptide-1 Receptor Agonists Use Does Not Increase the Risk for Acute Pancreatitis and Is Associated with Lower Complications in Patients with Type 2...
[American Journal of Gastroenterology] A retrospective cohort study was performed using population-based data from the TriNetX platform. T2DM patients receiving GLP-1 RAs drugs between January 1, 2015, and October 31, 2023 were included.
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Effects of Bisphenol A and Retinoic Acid Exposure on Neuron and Brain Formation: a Study in Human Induced Pluripotent Stem Cells and Zebrafish Embryos
[Environmental Health Perspectives] The authors used hiPSCs and zebrafish embryos to investigate whether co-exposure to bisphenol A and exogenous retinoic acid (RA) can potentiate HOX gene expression and exert pleiotropic effects on RA signaling.
IPS HEART Granted Orphan Drug Designation in the EU for Becker Muscular Dystrophy
[IPS Heart (Businesswire)] IPS HEART has been awarded orphan drug designation in the EU by the European Medicines Agency for GIVI-MPCs unique ability to create new muscle with 100% full length dystrophin in Becker Muscular Dystrophy.
Proteogenomic Reprogramming to a Functional Human Blastomere-Like Stem Cell State via a PARP-DUX4 Regulatory Axis
[Cell Reports] Investigators showed that conventional hPSCs cultured with non-specific tankyrase-PARP1-inhibited conditions underwent proteogenomic reprogramming to functional blastomere-like tankyrase/PARP inhibitor-regulated naive stem cells.
