Noshin Noorjahan

[Advanced Materials] Scientists hypothesized that ECM softening in periodontal disease contributes to inflammation by dysregulating gingival fibroblasts.

[Nature Communications] Researchers showed that the ECM component hyaluronan mediates adherens junction-independent circulating tumor cell clustering in triple-negative breast cancers.

[Bone Research] Deletion of Foxi3 in the mouse cranial neural crest cells (CNCCs) did not disrupt mandible and auricular development, further confirming that FOXI3 does not directly regulate CNCCs.

[Current Biology] Investigators identified a novel calcium signaling axis involving the mechano-gated channel transient receptor potential vanilloid 4 (TRPV4), which regulates lamellipodial protrusions in various cell types.

[Biochimica Et Biophysica Acta-Molecular Cell Research] Scientists identified nuclear prelamin A recognition factor (NARF) as a novel matrix stiffness-responsive gene, whose transcription is directly regulated by the mechanosensor Yes-associated protein.

[Scientific Reports] The authors investigated the histopathological, biochemical, and molecular effects of topical esculin on full-thickness wounds in streptozotocin-induced diabetic rats.