Global O-GlcNAcylation Changes Impact Desmin Phosphorylation and Its Partition Toward Cytoskeleton in C2C12 Skeletal Muscle Cells Differentiated Into Myotubes

In a model of C2C12 myotubes, researchers modulated the global O-GlcNAcylation level, and they determined whether the expression, the post-translational modifications and the partition of desmin toward insoluble material or cytoskeleton were impacted or not.