Newsletters

[Josep Carreras Leukemia Research Institute] Dr. Josep Maria Ribera, head of the Acute Lymphoblastic Leukaemia laboratory at the Josep Carreras Leukemia Research Institute, has been awarded the prestigious EHA Clinical Excellence Award 2026.

[Nature] Investigators developed xenograft inflammation–recovery models and performed single-cell multiomics on xenografted human hematopoietic stem cells.

[Leukemia] Scientists studied sphingosine-1-phosphate and FLT3 co-targeting to overcome FLT3 inhibitor resistance in NRAS-mutated FLT3-ITD AML cells.

[Leukemia] Researchers reported the design of a novel anti-hCD7 mAb-based antibody-drug conjugate carrying a BCL-XL-selective inhibitor that circumvents this significant limitation.

[Cell Reports] Scientists showed that chronic Salmonella infection significantly impair stem and progenitor cells of the bone marrow. As early as 14 days post-infection, the transplantation potency of HSC is depleted.

[Blood] Researchers analyzed 688 intensively treated NPM1-mutated AML integrating variant allele frequency, mutation order, and clonal architecture inferred by PyClone and ClonEvol.

[American Journal of Hematology] Investigators conducted a multicenter, retrospective analysis of 66 patients diagnosed with VEXAS syndrome treated with hypomethylating agents or allogeneic HSC transplantation.

[npj Precision Oncology] The authors used transcriptome analyses of primary AML cohorts and identified BEN domain-containing protein 4 (BEND4) as significantly overexpressed in adverse cytogenetic risk.

[npj Precision Oncology] Scientists provide a comprehensive overview of the evolving landscapes of immunotherapeutic strategies, challenges, and breakthroughs in tackling AML.

[International Journal of Oral Science] Researchers demonstrated that the pluripotency regulator octamer-binding transcription factor 4 (OCT4) promoted odontogenic differentiation by activating period circadian regulator 1 (PER1) in replicative senescent stem cells from apical papilla (SCAP) spheres.

[ACS Nano] Scientists established an analytical toolbox comprising scattering and fluorescence mode nanoparticle tracking analysis, fluorescence-based flow cytometry, and multidetector analytical size-exclusion chromatography.

[ACS Applied Materials & Interfaces] Researchers presented a type of multifunctional inverse opal nerve guidance conduit integrating bone marrow MSCs for peripheral nerve repair.