Integrated Proteomic Analysis to Explore the Molecular Regulation Mechanism of IL-33 mRNA Increased by Black Carbon in the Human Endothelial Cell Line EA.hy926

The authors identified that BC induced mitochondrial damage and suppressed autophagy function in EA.hy926 cells, as evidenced by elevation of the aspartate aminotransferase, reactive oxygen species, and p62, and the reduction of mitochondrial membrane potential.