Aspirin Modulates Succinylation of PGAM1K99 to Restrict the Glycolysis through NF-κB/HAT1/PGAM1 Signaling in Liver Cancer

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Investigators found that aspirin attenuated the phosphoglycerate mutase 1 (PGAM1) succinylation to suppress the PGAM1 enzymatic activities and glycolysis in hepatoma cells.
[Acta Pharmacologica Sinica]
Abstract