SLAMF1 Is Expressed and Secreted by Hepatocytes and the Liver in Non-alcoholic Fatty Liver Disease

To test whether signaling lymphocytic activation molecule 1 (SLAMF 1) was expressed by hepatocytes, scientists treated HepG2 cells and primary murine hepatocytes with palmitic acid to induce a state of lipotoxicity mimicking non-alcoholic steatohepatitis.