Mesenchymal Stem Cells Improve Liver Fibrosis and Protect Hepatocytes by Promoting microRNA-148a-5p-Mediated Inhibition of Notch Signaling Pathway

Scientists demonstrated that human umbilical cord mesenchymal stem cells treatment inhibited hepatic stellate cells activation, protected hepatocytes, and alleviate bile duct ligation-induced liver fibrosis in mice by up-regulating the expression of miR-148-5p and inhibiting the Notch signaling pathway.