Phenotypic Heterogeneity Driven by Plasticity of the Intermediate EMT State Governs Disease Progression and Metastasis in Breast Cancer

Investigators isolated multiple distinct single-cell clones from the SUM149PT human breast cell line spanning the epithelial-to-mesenchymal transition spectrum having diverse migratory, tumor-initiating, and metastatic qualities, including three unique intermediates.
[Science Advances]
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