Platelet-Inspired Intravenous Nanomedicine for Injury-Targeted Direct Delivery of Thrombin to Augment Hemostasis in Coagulopathies

Scientists reported on the design and evaluation of thrombin-loaded injury-site-targeted lipid nanoparticles that could specifically localize at an injury site via platelet-mimetic anchorage to the von Willebrand factor and collagen.