CDK5RAP3 Acts as a Tumor Suppressor in Gastric Cancer through the Infiltration and Polarization of Tumor-Associated Macrophages

The absence of CDK5RAP3 in gastric cancer cells allowed macrophages to secrete more matrix metalloproteinase 2 to promote the epithelial-mesenchymal transition process of gastric cancer cells, thereby enhancing the invasion and migration ability.