PKM2 Promotes Pulmonary Fibrosis by Stabilizing TGF-β1 Receptor I and Enhancing TGF-β1 Signaling

Researchers demonstrated that pyruvate kinase M2 promoted pulmonary fibrosis progression by directly interacting with Smad7 and reinforcing transforming growth factor–β1 (TGF-β1) signaling.
[Science Advances]
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