Macrophages Release IL11-Containing Filopodial Tip Vesicles and Contribute to Renal Interstitial Inflammation

Researchers showed that macrophage filopodia produced a unique membrane structure called “filopodial tip vesicle” (FTV) that originated from the tip of macrophages filopodia, contained numerous internal-vesicles, and functioned as cargo storage depots via nanotubular transport.