A Pancreatic Cancer Organoid-in-Matrix Platform Shows Distinct Sensitivities to T Cell Killing

Investigators described an INTERaction with Organoid-in-MatriX model system, that presentd a 3D co-culture-based platform for investigating matrix-dependent cellular crosstalk. They describe its potential to uncover new molecular mechanisms of T cell responses to murine KPC pancreatic ductal adenocarcinoma (PDAC) cells as well as PDAC patient-derived organoids.