JK-1, a Useful Erythroleukemic Cell Line Model to Study a Controlled Erythroid Differentiation from Progenitors to Terminal Erythropoiesis

Using an epigenetic differentiation inhibitor that keeps JK-1 in an early differentiation phase, investigators characterized 2 progenitor stages: BFU-E JK-1 and CFU-E JK-1 with CD34+/CD36− and CD34−/CD36+ phenotypes respectively.