In Vivo Production of an Anti-HIV Antibody in Mice by Non-Viral Gene Knock-In in Primate Hematopoietic Stem and Progenitor Cells

Researchers evaluated CRISPR/Cas9 and CRISPR/Cas12a for gene knock-in at the immunoglobulin heavy chain locus in non-human primate hematopoietic stem and progenitor cells.