Newsletters

[Clinical and Experimental Medicine] Experimental validation researchers confirmed the significantly downregulation of BCAT2 in the lung tissues of IPF patients and in TGF-β1-treated alveolar epithelial cells

[Scientific Reports] Scientists investigated cold-inducible RNA-binding protein's function using an in vivo bleomycin-induced pulmonary fibrosis mouse model via intratracheal administration and an in vitro model with primary lung fibroblasts.

[PloS One] Researchers investigated whether human and rat pulmonary fibroblasts, when stimulated with TNF-α and IL-4, acquire lymphangiogenic and antifibrotic properties.

[Cancer Discovery] Investigators used mouse and human models to deconstruct the transcriptional programs and sequelae underlying robust therapeutic responses in lung adenocarcinoma.

[ACS Nano] Scientists reported a recombinant targeted bionanoparticle that in vitro expresses Cas9 protein, tBioNP vitro-Cas9, for gene editing of epidermal growth factor receptor mutant lung cancer.

[Cancer Cell International] The authors assessed the cell viability, proliferation, colony formation, and intracellular lipid droplet accumulation of Nine NSCLC cell line treated with tinzaparin, cisplatin, or a combination.

[Clinical and Experimental Medicine] Investigators reported that PRKD1 negatively regulates β-catenin protein abundance. PRKD1 promoted ubiquitination and degradation of EIF5A.

[Scientific Reports] Researchers performed RNA sequencing to identify differentially expressed circRNAs in small cell lung cancer compared with normal lung tissue.

[Scientific Reports] 119 cases of NSCLC tissue specimens were used to determine the expression levels and prognostic values of IL-7, IL-7R, E-cadherin and Vimentin.

[Free Radical Research] Scientists investigated the mechanism of METTL7B-medaited m6A modification in NSCLC cell ferroptosis. NSCLC cells, SK-MES-1/PC9/H1975/A549, and normal cells, BEAS-2B, were cultured.

[Cancer Cell International] The authors explore the molecular mechanisms by which IGF2BP3 contributes to lung cancer development and progression, and to discuss its potential applications in diagnosis, prognostic assessment, and therapeutic strategies.

[Respiratory Research] Scientists describe lactate metabolism and the discovery of lactylation, and discuss recent findings related to their role in the pathogenesis of lung diseases.