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Prostate Cell News
Prostate Cell News is an online resource summarizing the latest prostate cell research.
Transcriptional Analysis of Metastatic Hormone-NaïVe Prostate Cancer Primary Tumor Biopsies Reveals a Relevant Role for SOX11 in Prostate Cancer Cell Dissemination
[Genome Biology] Scientists provided the first extensive transcriptomics characterization of primary tumor specimens from patients with metastatic hormone-naïve prostate cancer.
Unraveling the Efficacy of AR Antagonists Bearing N-(4-(Benzyloxy)Phenyl)Piperidine-1-Sulfonamide Scaffold in Prostate Cancer Therapy by Targeting LBP Mutations
[Journal of Medicinal Chemistry] Researchers developed a compound, which contains an N-(4-(benzyloxy)phenyl)piperidine-1-sulfonamide scaffold through structural optimization and comprehensive screening against T878A-mutated androgen receptor.
Pericytes in Castration-Resistant Prostate Cancer Associated with Disease Progression and Immunotherapy Response: Insights from Single-Cell Analysis
[Cancer Cell International] Researchers decipher the biological effects of pericytes on castration-resistant prostate cancer and their interactions with the tumor microenvironment.
A Fluorescent Probe Targeting EGFR for the Stratification of Prostate Cancer Cells
[Journal of Molecular Biology] Scientists designed a competitive, modular fluorescent probe targeting the oncogenic epidermal growth factor receptor (EGFR) kinase and was utilized for probe-based cytometry to subtype urine samples from prostate cancer patients.
Evaluating PSA Dynamics for Predicting Androgen Deprivation Failure with a Patient Specific Prostate Cancer Model
[NPJ Systems Biology and Applications] Investigators presented a data-driven mathematical modeling approach that integrates patient-specific prostate-specific antigen (PSA) time-course data with experimentally measured PSA expression rates to improve the prediction of androgen deprivation therapy failure.
POLR2H Serves As a Novel Prognostic Biomarker Correlated with Immune Infiltration in Prostate Cancer
[Biochemical Genetics] Investigators explored the prognostic value and potential functions of POLR2H in prostate cancer.
Liquid Biopsy for Promoter Methylation in Prostate Cancer: A Promising Non-Invasive Diagnostic Weapon
[World Journal of Urology] The authors assess the diagnostic accuracy of liquid biopsy for promoter methylation in prostate cancer.
US FDA Approves Third Indication of Darolutamide for Patients with Advanced Prostate Cancer
[Orion Pharma] Orion’s collaboration partner Bayer announced that the US FDA has approved the oral androgen receptor inhibitor darolutamide in combination with androgen deprivation therapy for use in patients with metastatic castration-sensitive prostate cancer.
Mitochondrial SLC25A10 Promotes Prostate Cancer Progression by Inhibiting Ferritinophagy
[Cell Death Discovery] Investigators systematically analyzed transcriptomic data from The Cancer Genome Atlas and performed Venn analysis to identify genes associated with prostate cancer progression.
Characterization of RNA Editing Gene APOBEC3C As a Candidate Tumor Suppressor in Prostate Cancer
[Scientific Reports] Researchers evaluated RNA-editing genes in prostate cancer (PCa). Notably, the APOBEC3 genes are clustered in terms of their chromosomal locations, and their transcriptional changes exhibit significant positive correlations in both primary PCa and castration-resistant prostate cancer
Significance of Androgen Receptor and Its Potential for Anti-Androgen/Androgen Receptor-Antagonist Therapy in Ovarian Cancers
[PLOS One] Researchers evaluated androgen receptor expression among different types of ovarian cancers and compared the results to estrogen and progesterone receptors.
Therapeutic Efficacy of Melatonin and Flutamide Combination in Safety for Prostate Cancer: An In Vitro Study
[DNA and Cell Biology] Investigators evaluated the effect of melatonin, flutamide, and melatonin–flutamide combination therapy in LNCaP, DU145, and PC3 cell lines.
Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.
