BDNF

[Scientific Reports] Researchers examined blood–brain barrier disruption, by assessing brain-derived neurotropic factor, neuron-specific enolase levels, and gut-blood barrier disruption by trimethylamine N-oxide in chronic kidney disease patients.

[Cancer Letters] Researchers investigated the interaction of ras-related protein in brain (Rab8A) and tropomyosin-related kinase B in regulating the progression of breast cancer. Rab8A was upregulated in breast cancer tissues.

[Science Advances] Scientists reported that at 24 hours after ischemia, microglia released brain-derived neurotrophic factor to downregulate glutamatergic and GABAergic synapses within the peri-infarct area.

[Cell and Tissue Research] In vitro functionality testing showed that these expanded cells promoted angiogenesis and, in brain glial cells, promoted cell proliferation and reduced production of reactive oxygen species during oxidative stress.

[Scientific Reports] Scientists compared the neurogenic ability of dental pulp stem cells to bone marrow-derived MSCs under inflammatory stimulation.

[Acta Pharmacologica Sinica] The authors identified a natural product patchouli alcohol as a selective estrogen receptor β agonist which improved the cognitive defects in female APP/PS1 mice, and explored the underlying mechanisms.