GABAergic

[Molecular Psychiatry] The authors reported that FOXG1 was expressed in the main adult neurogenic niches in mice, i.e. the hippocampal dentate gyrus and the subependymal zone/olfactory bulb system, where neurogenesis of glutamatergic and GABAergic neurons persisted into adulthood.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists identifed a synaptogenic/growth-promoting role for microglia in regulating pyramidal neuron axon initial segment (AIS) synapse formation by chandelier cells, a unique interneuron subtype whose axonal terminals, called cartridges, selectively targeted the AIS.

[Science Advances] Scientists reported that at 24 hours after ischemia, microglia released brain-derived neurotrophic factor to downregulate glutamatergic and GABAergic synapses within the peri-infarct area.

[Nature] Scientists used organoid models of the human cerebral cortex to identify cell-type-specific developmental abnormalities that result from haploinsufficiency in three autism spectrum disorder risk genes—SUV420H1, ARID1B and CHD8—in multiple cell lines from different donors.

[Scientific Reports] Researchers provided a proof-of-concept that human embryonic stem cell-derived neurons could integrate and modulate the activity of a human host neuronal network.

[Molecular Psychiatry] Scientists review the existing experimental and translational research pinpointing the complex dynamics of oxidative stress mechanisms and their modulation in relation to schizophrenia pathophysiology.