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HUVECs

PEDF Is an Endogenous Inhibitor of VEGF-R2 Angiogenesis Signaling in Endothelial Cells

[Experimental Eye Research] Scientists showed that pigment epithelium derived factor (PEDF) prevented early mitogenic signals of vascular endothelial growth factor in primate retinal endothelial cells, blocking proliferation, migration and tube formation.

Novel Human Placenta-Based Extract for Vascularization Strategies in Tissue Engineering

[Tissue Engineering Part C-Methods] The authors described an effective method of isolating a human placenta substrate that induced the spontaneous formation of an interconnected network of green fluorescence labeled HUVECs in vitro.

Antiangiogenic Antibody BD0801 Combined with Immune Checkpoint Inhibitors Achieves Synergistic Antitumor Activity and Affects the Tumor Microenvironment

[BMC Cancer] The anti-cancer activities of BD0801 and its potential synergistic anti-tumor effects when combined with different immunotherapies were assessed by using in vitro assays and in vivo tumor models.

Functional Characterization of a Bioengineered Liver after Heterotopic Implantation in Pigs

[Communications Biology] Researchers reported a method for seeding and engrafting primary porcine hepatocytes into a bioengineered liver scaffold previously reendothelialized with human umbilical vein endothelial cells.

Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity

[Circulation Research] HUVECs were exposed to either laminar flow or oscillating disturbed flow for 24 hours in a cone-and-plate device.

Bovine Milk Exosomes Alleviate Cardiac Fibrosis via Enhancing Angiogenesis In Vivo and In Vitro

[Journal of Cardiovascular Translational Research] The proangiogenic effect of bovine milk exosomes was analyzed both in isoproterenol-induced cardiac fibrosis rats in vivo and in HUVECs after oxygen and glucose deprivation in vitro.

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