ductal carcinoma

[Scientific Reports] The authors determined the clinical and functional relevance of CCL2/CCR2 signaling proteins to ductal carcinoma in situ progression.

[Scientific Reports] A new spontaneously immortalized breast cancer cell line, DHSF-BR16 cells, was isolated from the primary invasive ductal carcinoma of a 74-years old female patient, treated with neoadjuvant chemotherapy and disease-free 5-years after adjuvant chemotherapy.

[Cancer Gene Therapy] Scientists investigated the possible effects KDM3B-ETF1 fusion gene had on breast cancer cell metastasis, invasion and its downstream signaling mediators as revealed from RNA sequence data analysis.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers subjected low-glycolytic breast cancer cells to different microenvironmental selection pressures using combinations of hypoxia, acidosis, low glucose, and starvation for many months and isolated single clones for metabolic and transcriptomic profiling.

[Oncogene] Human breast cancer cell culture models revealed that siRNA-mediated silencing of transmembrane protease, serine 13 (TMPRSS13) expression decreased proliferation, induced apoptosis, and attenuated invasion.

[npj Breast Cancer] Investigators performed subtype stratified analyses and identified key differences between ductal carcinoma in situ and invasive breast cancer that suggested subtype specific progression.