endothelial cells

[Journal of Molecular and Cellular Cardiology] By administration of new techniques, including genetic cell lineage tracing and single cell RNA sequencing, more solid data were obtained that support the concept of stem/progenitor cells for regenerating damaged endothelium.

[Cell Death & Disease] Researchers explored the role of endothelial progenitor cells derived extracellular vesicles transmitting Taurine upregulated gene 1 in macrophage polarization and macrophage-mediated inflammation in a cecal ligation and puncture-induced sepsis mouse model.

[Experimental Eye Research] Scientists showed that pigment epithelium derived factor (PEDF) prevented early mitogenic signals of vascular endothelial growth factor in primate retinal endothelial cells, blocking proliferation, migration and tube formation.

[Bioengineered] Lipopolysaccharide was used to induce AUI in mice models and EPCs to mimic the realistic pathogenesis of intrauterine adhesion in vivo and in vitro.

[Molecular Medicine Reports] Researchers explored the role and molecular mechanisms underlying Netrin‑1 in the viability and angiogenic function of EPCs. The apoptosis and various functions of EPCs were analyzed in vitro by manipulating the expression of Netrin‑1.

[Molecular Medicine Reports] Chronic hypertension can lead to kidney damage, known as hypertensive nephropathy or hypertensive nephrosclerosis. The authors investigated the mechanisms by which endothelial progenitor cells repaired primary rat kidney cells.