endothelial cells

[Scientific Reports] Scientists analyzed the endothelial function, molecular signature, and mitochondrial profile of chronic thromboembolic pulmonary hypertension (CTEPH)-derived endothelial cells to better understand the pathophysiological mechanisms of endothelial dysfunction behind CTEPH.

[Journal of Cellular and Molecular Medicine] The authors investigated the consequences of interaction between placenta MSCs and platelets, and its impact on platelet-mediated atherosclerosis in vitro.

[Fluids and Barriers of the CNS] Investigators applied a novel bioengineering approach to generate human blood-brain barrier organoids by the self-assembly of astrocytes, pericytes and brain endothelial cells with unprecedented throughput and reproducibility using micro patterned hydrogels.

[Angiogenesis] Chemerin did not affect vascular sprouting during the post-natal development of the network, but rather promoted endothelial cell apoptosis and vessel pruning.

[Phytotherapy Research] Scientists analyzed the inhibitory effects of AA on angiogenesis using HUVECs cultured in vitro and on the growth and metastasis of a subcutaneous breast cancer 4T1 tumor model and a lung metastasis model in vivo.

[Journal of Molecular and Cellular Cardiology] Investigators performed single-cell profiling of 35,245 cells from two venous malformation samples and three cavernous venous malformation samples, with a focus on endothelial cells, smooth muscle cells and immune microenvironment.