endothelial progenitor cells

[EMBO Reports] Researchers showed that pervasive and dynamic alternative splicing takes place during hematopoietic development of human pluripotent stem cells. They identified a splicing factor switch that occurs during the differentiation of mesodermal cells to endothelial progenitor cells.

[Experimental Cell Research] Dynamic interactions between specific organ endothelial cells and different cellular components are crucial for different organ morphogenesis and function. Conversely, organs provide cues shaping vascular network structure.

[Journal of Materials Science-Materials in Medicine] Umbilical-cord blood vessels were isolated for decellularization and to establish endothelial cell culture. Cultured cells were characterized by immunophenotype, gene expression and in vitro angiogenesis assay.

[Cell Death & Disease] Scientists review the potential mechanism of stem cells as new therapeutic agents in the treatment of diabetic nephropathy (DN). They also review recent findings and updated information about not only the utilization of stem cells on DN in both preclinical and clinical trials but limitations and future expectations of stem cell-based therapy for DN.

[BMC Pulmonary Medicine] Scientists characterized of the CD34+ cell population in peripheral blood in patients with sarcoidosis (SA) with reference to the control group. Moreover in patients with SA, fibrocytes and endothelial cells were analyzed and their relationship to the fibrosis process based on assessment of diffusing capacity for carbon monoxide.

[Experimental Cell Research] Mice were subjected to exercise training for four weeks. Bone marrow-derived endothelial progenitor cells (EPCs) were isolated and cultured in vitro. Exercise upregulated miR-126 expression but downregulated the protein levels of its target gene, Spred1, in EPCs from myocardial infarctionmice.