hepatic cells

[Stem Cell Research & Therapy] Researchers evaluated the potential and feasibility to identify proliferating human hepatocytes from primary human hepatocytes with Raman spectroscopy.

[International Journal of Stem Cells] Investigators introduced a rat model of liver fibrosis and trans-portal transplantation of human liver stem cells to demonstrate alleviation of liver fibrosis.

[Journal of Hepatology] Scientists investigated the expression and function of annexin A11 in human cholangiocytes and a potential role of IgG1/IgG4-mediated autoreactivity against annexin A11 in the pathogenesis of IgG4-related cholangitis.

[Journal of Gastroenterology and Hepatology] The autophagy attenuation exerted by chloroquine together with the reduction of the expression of the proliferation marker in hepatic stellate cells could lessen the acute liver damage, potentially opening the way to novel therapeutic approaches for hepatic fibrosis.

[iScience] To obtain a cellular resolution of pathogenesis, 82,168 single-cell transcriptomes across different nonalcoholic fatty liver disease stages were profiled, identifying hepatocytes and 12 other non-parenchymal cell types.

[Heliyon] Scientists investigated the apoptotic capacity of GenX in human liver cells. When representative human-derived liver cells (HepG2 cells) were treated with GenX for 12 hours, cell viability was reduced, and apoptosis was greatly increased.