hepatic stellate cells

[Cell Death & Disease] Researchers studied the proferroptosis effect and mechanism of mesenchymal stem cell-ex in hepatic stellate cells.

[Cell Death & Disease] Researchers investigated the functional subsets of γδ T cells in hepatic fibrosis and to further explore the underlying causes and drivers of migration.

[Scientific Reports] Researchers engineered cell sheets to develop a new in vitro model of ballooned hepatocytes.

[Nature Communications] Scientists reported a targeted antifibrotic peptide-delivery system in which fibroblast activation protein, which was overexpressed in fibrotic regions of the liver, liberated the antifibrotic peptide melittin by cleaving a fibroblast activation protein-specific site in the peptide.

[Journal of Hepatology] Researchers investigated the role of X-box binding protein-1 (XBP1) in the progression of non-alcoholic steatohepatitis.

[Cell Death & Disease] The authors demonstrated the involvement of hepatic stellate cell-derived hydrogen sulfide (H2S) in JNK/JunB mediated expression of TNFSF14 gene, which indicated that H2S played an important role in the regulation of HCC apoptosis.