pancreatic cancer cells

[International Journal of Molecular Sciences] The authors address the current molecular biological features for understanding the multifactorial function of PARP-1 in pancreatic cancer related to the aforementioned roles, along with the summary of recent approaches with PARP-1 inhibition in clinical studies targeting pancreatic cancer.

[Cell Death & Disease] The role of miR-30d in the proliferation and metastasis of pancreatic cancer cells was determined using in vitro and in vivo assays.

[Biochemical and Biophysical Research Communications] Scientists compared PANC-1 and MIA PaCa-2 pancreatic cancer cells which are, respectively, resistant and sensitive to MEK- and PI3K-targeted therapy.

[Scientific Reports] Researchers explored multifunctional nanobubbles named IR780-NBs-DTX as novel ultrasound contrast agents for dual-mode targeted imaging and photothermal ablation combined with chemotherapy for pancreatic cancer.

[Experimental and Molecular Medicine] The authors analyzed the relation between pancreatic cancer-derived pancreatic adenocarcinoma upregulated factor and cancer cachexia in mice and its clinical significance.

[Scientific Reports] Investigators demonstrated that delivery of oxidized Coenzyme Q10 increased mitochondrial Q-pool and was associated with an increase in reactive oxygen species (ROS) generation, effectuating anti-cancer effects in a pancreatic cancer model.