prostate cells

[Journal of Human Genetics] Using genome-wide target capture of miRNAs and miRNA-binding sites followed by deep sequencing in prostate cancer cell lines, researchers identified prostate cancer-specific single nucleotide variants in mature miRNAs and their target binding sites.

[Scientific Reports] Scientists explored the mechanism of action of Maytenus royleanus (MEM) in prostate cancer (PCa) by employing an in vitro global proteome approach to get useful information of various signaling pathways and effected genes to define the mechanism of MEM action in Pca.

[Scientific Reports] Treatment of C4-2 cells with the 4F2 cell-surface antigen heavy chain was found to suppress cellular growth, migratory and invasive abilities, with this effect occurring through the cell cycle, with a significant decrease in S phase and a significant increase in G0/G1 phase, suggesting cell cycle arrest.

[Molecular Oncology] Researchers found that depletion of either FKBP51 or FKBP52 reduced androgen receptor(AR) dimer formation, chromatin binding and phosphorylation, suggesting defective AR signaling.

[Molecules] Anti-cancer activity of catechin nanoemulsions prepared from Oolong tea leaf waste was studied on prostate cancer cells DU-145 and DU-145-induced tumors in mice.

[Scientific Reports] Investigators observed and investigated the mechanism of induction of SLCO1B3 by abiraterone. Prostate cancer cells were treated with anti-androgens and assessed for SLCO1B3 expression by qPCR analysis.