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prostate cells

Novel Indazole Skeleton Derivatives Containing 1,2, 3-Triazole as Potential Anti-Prostate Cancer Drugs

[Bioorganic & Medicinal Chemistry Letters] The antiproliferative activity of target compounds in four human cancer cells, PC-3 (human prostate cancer cell), MCF-7 (human breast cancer cell), HepG-2 (human hepatoma cell) and MGC-803 (human gastric cancer cell), was evaluated by thiazole blue.

Ets-Related Gene (ERG) Undermines Genome Stability in Mouse Prostate Progenitors via Gsk3β Dependent Nkx3.1 Degradation

[Cancer Letters] By combining organoids technology with Click-chemistry coupled Mass Spectrometry, investigators demonstrate a prominent role of ERG in remodeling the protein secretome of prostate progenitors.

Application of Surface-Enhanced Raman Spectroscopy to Guide Therapy for Advanced Prostate Cancer Patients

[ACS Sensors] Investigators demonstrated a linear calibration curve from cell lysate and correlate lysate protein with mRNA from cultured prostate cancer cells.

Microcystin-Lr Induced Microfilament Rearrangement and Cell Invasion by Activating Erk/Vasp/Ezrin Pathway in DU145 Cells

[Toxicon] Scientists investigated the effect of Microcystin-LR on prostate cancer cell invasion and its underlying mechanisms.

Radiotherapy Alters Expression of Molecular Targets in Prostate Cancer in a Fractionation- and Time-Dependent Manner

[Scientific Reports] The authors irradiated prostate cancer cells either with a single dose of 10 Gy x-ray or a multifractionated regimen with 10 fractions of 1 Gy.

LXA4 Enhances Prostate Cancer Progression by Facilitating M2 Macrophage Polarization via Inhibition of METTL3

[International Immunopharmacology] Scientists showed that downregulation of METTL3 in prostate cancer tumor-associated macrophages modulated macrophages toward an M2-like phenotype and that this modulation was mediated by activation of STAT6.

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