Publication

[Nature Communications] Researchers reported that the lncRNA INHEG was highly expressed in glioma stem cells (GSCs) compared to differentiated glioma cells and promoted GSC self-renewal and tumorigenicity through control of rRNA 2’-O-methylation.

[Cell Reports] Scientists identified that stabilizing vimentin phosphorylation at serine 56 induces multinucleation, specifically in hybrid epithelial-mesenchymal cells with stemness properties but not epithelial or mesenchymal cells.

[eLife] Researchers investigated whether the combination of three markers, EpCAM, CD24, and Vimentin, could identify disseminating epithelial-mesenchymal transition CSCs in actual human tumors.

[Journal of Translational Medicine] Scientists revealed the critical mediators that regulated glycolytic metabolism reprogramming in gastric cancer and their underlying molecular mechanism.

[International Journal Of Radiation Oncology Biology Physics] The authors found that NK cells in combination with tumor irradiation may provide synergistic therapeutic effects for NK cell recognition and elimination against both parental and stem-like liver cancer through lymphocyte function-associated antigen 1/intercellular adhesion molecule-1.

[Carcinogenesis] Investigators characterized how esophageal squamous cell carcinoma and preneoplastic cells respond to alcohol exposure using cell lines, three dimensional organoids, and xenograft models.