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Bitter Taste Receptors in the Reproductive System: Function and Therapeutic Implications

[Journal Of Cellular Physiology] In the uterus, TAS2Rs contribute to uterine relaxation and hold potential as therapeutic targets for preventing preterm birth. In the placenta, they are proposed to function as vigilant sentinels, responding to infection and potentially modulating mechanisms of fetal protection.

Liver Sinusoidal Endothelial Cells As Potential Drivers of Liver Fibrosis

[Molecular Medicine Reports] Scientists summarized changes in liver sinusoidal endothelial cells (LSECs) during liver fibrosis and their interactions with hepatic milieu, as well as possible therapeutic approaches that specially target LSECs.

Pyroptosis: A Double-Edged Sword in Lung Cancer and Other Respiratory Diseases

[Cell Communication And Signaling] Emerging evidences have shown that pyroptosis contributes to many pulmonary diseases, especially lung cancer, and pneumonia. Scientists review the multifaceted roles of pyroptosis in respiratory diseases.

The Impact of Induced Pluripotent Stem Cells in Animal Conservation

[Veterinary Research Communications] The authors focus on the progress made with iPSC lines derived from endangered and extinct species, exploring their potential applications and limitations in animal welfare research.

The Roles and Regulatory Mechanisms of TGF-β and BMP Signaling in Bone and Cartilage Development, Homeostasis and Disease

[Cell Research] Scientists weave the background information with the latest advances in the signaling facilitated by transforming growth factor-βs (TGF-βs) and bone morphometric proteins (BMPs), and the advanced understanding of their diverse physiological functions and regulations.

Endothelial Dysfunction and Cardiovascular Diseases: The Role of Human Induced Pluripotent Stem Cells and Tissue Engineering

[Journal Of Biomedical Materials Research Part A] The authors provide a brief introduction to cardiovascular disease, reviewing some of the recent studies as related to the role of endothelial cells and endothelial cell dysfunction.

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