Review

[Trends in Microbiology] The authors explore the latest advances in CRISPR-Cas-based approaches to elucidate virus–host interactions, focusing on the identification of key receptors and host factors essential for virus infection.

[Trends in Pharmacological Sciences] Scientists provide an overview of the inherent characteristics of oncolytic herpes simplex virus type 1 (HSV-1) as a gene delivery platform, focusing on its genetic modification strategies, safety challenges in clinical applications, and future directions to maximize its therapeutic potential.

[Medicinal Research Reviews] The authors manifest overall information regarding the effects of phytoestrogen on TNBC, along with its related cellular and molecular pathways in different TNBC models.

[Biomarker Research] Investigators highlight the benefits of utilizing single domain antibody in CAR-T therapy, particularly in targeting tumor antigens, and explore development strategies that could advance the field.

[Gastroenterology Report] Investigators provide a comprehensive analysis of the literature on exocrine pancreatic insufficiency etiology, with a thorough overview to support its consideration as a potential diagnosis.

[Molecular Therapy] The authors highlight the key milestones in CAR-T cell evolution, from its invention to its clinical applications.