Review

[Virology Journal] The authors explore the potential of adeno-associated virus (AAV) vectors as versatile tools for targeted gene therapy (GT) in HCC. They encapsulate the multifaceted exploration of AAV vectors in HCC GT, underlining their transformative potential within the landscape of oncology and human health.

[Cancer Science] Scientists discuss ex vivo culture protocols for expanding human HSCs and present the results of clinical trials using these techniques, along with future perspectives.

[Journal Of Experimental Medicine] Investigators discuss the major process parameters of autologous CAR-T cell manufacturing, as well as regulatory considerations and ongoing developments that will enable the next generation of CAR-T cell therapies.

[Nature Reviews Neurology] The authors present the current evidence for and understanding of inflammasome activation in neurological diseases and discuss current and potential interventional strategies that target inflammasome activation to mitigate its pathological consequences.

[Neurochemical Research] The authors summarize the production and function of IL-6 as well as its downstream signaling pathways. Moreover, they provide a comprehensive review of the roles of IL-6 in neurodegenerative disorders and its potential clinical application.

[Current Opinion In Cell Biology] Scientists discuss recent studies that have shone light on how ECM deposition and organization and the resulting mechanical and chemical signals contribute to modulating cell migration.