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Quemeiteng Granule Relieves Goiter by Suppressing Thyroid Microvascular Endothelial Cell Proliferation and Angiogenesis via miR-217-5p-Mediated Targeting of FGF2-Induced Regulation of the ERK Pathway

[Journal Of Ethnopharmacology] Scientists investigated the therapeutic effects of Quemeiteng granule on goiter and the downstream regulatory mechanisms. The viability of rat thyroid microvascular endothelial cells and human thyroid microvascular endothelial cells was assessed using the CCK-8 assays.

An Antitumor Arabinan from Glehnia littoralis Activates Immunity and Inhibits Angiogenesis

[International Journal Of Biological Macromolecules] GLP90–2 suppressed angiogenesis in the transgenic zebrafish model, and this impact may be ascribed to the modulation of the VEGF/VEGFR-2 signaling pathway.

Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution

[Circulation Research] Researchers used droplet-based single-cell RNA sequencing and multiplexed error-robust fluorescence in situ hybridization to define endothelial cells (EC) and EC progenitor subtypes from E9.5, E12.5, and E15.5 mouse embryos.

Integrated Single-Cell Transcriptomic Atlas of Human Kidney Endothelial Cells

[Clinical Journal Of The American Society Of Nephrology] Scientists identified five major cell types, 29,992 of which were endothelial cells. Endothelial cell re-clustering identified 7 subgroups that differed in molecular characteristics and physiological functions

Exosomes of Endothelial Progenitor Cells Repair Injured Vascular Endothelial Cells Through the Bcl2/Bax/Caspase-3 Pathway

[Scientific Reports] Researchers evaluated the influence of exosomes derived from endothelial progenitor cells (EPC-Exo) on neointimal formation induced by balloon injury in rats. They further investigated the potential of EPC-Exo to promote proliferation, migration, and anti-apoptotic effects of vascular endothelial cells in vitro.

Platelet Rich Fibrin as a Bioactive Matrix with Proosteogenic and Proangiogenic Properties on Human Healthy Primary Cells In Vitro

[Platelets] To further analyze the effect of platelet rich fibrin (PRF) on bone tissue regeneration, researchers investigated the influence of liquid PRF matrices on human healthy primary osteoblasts and co-cultures composed of pOB and human dermal vascular endothelial cells as in vitro model for bone tissue regeneration.

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