vitiligo

[Science Translational Medicine] Scientists report that patients with low melanoma neoantigen burdens who responded to ICI had tumors with higher expression of pigmentation-related genes.

[Pigment Cell & Melanoma Research] The authors summarize the latest insights into various forms of melanocytes death in vitiligo and discuss the corresponding mechanisms.

[Experimental Dermatology] Investigators discuss the pathways governing epithelial and follicular pigmentation, numerous areas of future research and potential points of intervention are highlighted.

[Pigment Cell & Melanoma Research] Investigators review the potential roles of the unfolded protein response/integrated stress response in the etiology of melanoma and vitiligo.

[Immunopharmacology and Immunotoxicology] The authors investigated the antioxidant effect of vitexin-activated mitogen-activated protein kinase-Nrf2/ARE axis in vitiligo.

[Diagnostics] Researchers found that p16ink4a immunoreactivity was not restricted to melanocytes but also existed in fibroblasts; the number of p16ink4a-positive fibroblasts was significantly increased in lesional skin compared to perilesional skin and normal controls.