[Nature Reviews Neuroscience] The authors consider whether axonal features could enable long-range and large-scale neuroplastic changes at a functional level, particularly following focal brain injury.

[University of Nottingham] Sidahmed Abayzeed, Assistant Professor in the Faculty of Engineering has received £200k for his project NeurOhmics – a platform that combines ultra-high-resolution optical microscopy based on electrical impedance and artificial intelligence for enhanced sensitivity.

[Cell Death Discovery] Scientists investigated the effects of Tetrandrine on SARS-CoV-2 infection in human lung epithelial cells, with a particular focus on autophagy-related mechanisms.

[Chinese Medical Journal] Researchers profiled the immune cell landscape in sepsis using scRNA-seq analysis, focusing on the significantly reduced naive CD4+ T cells.

[Proceedings of the National Academy of Sciences of the United States of America] The authors demonstrated that highly virulent Ebola virus induced a high and sustained pro-inflammatory response compared to less virulent ebolaviruses in non-mononuclear phagocytes through TLR4-independent NF-κB activation.

[Advanced Healthcare Materials] Researchers introduced a novel multiaxial bioreactor system that provided uniform stretching of skin grafts with continuous environmental monitoring capabilities.

[Biomacromolecules] Scientists developed a peptide-based, carrier-free topical delivery system that enhances hair growth while minimizing systemic exposure to finasteride.

[NPJ Biofilms and Microbiomes] The authors examine microbes from the skin, oral cavity, gut, urinary tract, and the prostate cancer microenvironment, summarizing how these communities affect prostate cancer initiation, progression, and therapeutic response.

[European Journal of Medical Research] Researchers investigated the role and mechanisms of pseudopodium-enriched atypical kinase (PEAK) 1 in prostate cancer progression and docetaxel resistance.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists identified circUTRN, an androgen receptor-inhibited circRNA that is upregulated following neoadjuvant hormonal therapy and downregulated in prostate cancer tissues.

[NPJ Vaccines] The authors explore mRNA-based vaccines as a promising immunotherapy in prostate cancer.

[Signal Transduction and Targeted Therapy] The authors provide an overview of the history and milestones in T cell exhaustion research, summarize the mechanisms of T cell exhaustion and its implications in cancer, chronic infections, and autoimmune diseases.