[Scientific Reports] Researchers analyzed the influence of radiotherapy on leucocyte telomere length in prostate cancer patients. A total of 314 patients treated with curative radiotherapy for prostate cancer were included in the present prospective study.

[Nature Reviews Urology] Understanding the clinical utility of circulating tumour cells (CTCs) and future innovations is crucial to incorporating CTCs into the clinical management of prostate cancer.

[Journal of Translational Medicine] The authors provide a comprehensive summary of current advances and persisting challenges in the field of prostate cancer immunotherapy.

[Science Advances] Using pharmacological and genetic interventions, researchers found that neutrophils within mature, necrotic granulomas promote bacterial growth, in part through up-regulation of the bacterial devR regulon.

[Emerging Microbes & Infections] Investigators evaluated SARS-CoV-2 spike-specific T cell responses among convalescents infected by three different strains against SARS-CoV-2 prototype and 15 subvariants covering all six serotypes.

[Penn Medicine] Perelman School of Medicine papers win Clinical Research Forum’s 2026 Top 10 Clinical Research Achievement Awards, highlighting the power of federal funding for science.

[Gastroenterology] Researchers found that F prausnitzii induces an anti-inflammatory response and rewires energy metabolism in human monocytes in healthy and inflamed conditions.

[JAMANeurology] In this cohort study of 111 patients with progressive multifocal leukoencephalopathy treated with immune checkpoint inhibitors, those with detectable virus-specific T cells had significantly higher response rates and longer survival than both T cell–negative patients and those with unknown status.

[Blood] Scientists investigated the role of Plasminogen/Plasmin on key features of inflammation resolution in a murine model of severe pneumococcal pneumonia.

[EMBO Molecular Medicine] Scientists reported that the human cytomegalovirus Fcγ-binding glycoprotein 34 modulates humoral immunity by binding to IgG⁺ memory B cells.

[Nature Immunology] The authors reported that encoding CD8 co-receptors in both Cd4 and Cd8 gene loci modulates major histocompatibility complex class I T cell antigen receptor signaling duration to generate all potential CD8+ T cell subsets.

[Cancer Immunology Research] In a murine lung cancer model induced by Lewis lung carcinoma cells, scientists found that P2RX7 enhanced the suppressive capacity of tumor-infiltrating Tregs, promoting tumor growth.