Fer Kinase Regulates Cell Migration through α-Dystroglycan Glycosylation Researchers’ results indicate that the Fer pathway negatively controls expression of genes required to synthesize laminin-binding glycans, thus impairing basement membrane attachment and increasing tumor cell migration. [Mol Biol Cell] Abstract Fibronectin Induces Endothelial Cell Migration through β1-Integrin and Src Dependent Phosphorylation of Fibroblast Growth Factor Receptor-1 at Tyrosines 653/654 and 766 Researchers demonstrate how differential phosphorylation profiles of fibroblast growth factor receptor-1 can achieve alternate downstream signals, and more broadly, highlight the diversity of mechanisms by which the extracellular matrix microenvironment regulates cell behavior through transactivation of receptor tyrosine kinases. [J Biol Chem] Abstract Nanofibrous Collagen Nerve Conduits for Spinal Cord Repair In this study, the potential application of electrospun collagen nanofibers for spinal cord injury treatment was evaluated in vitro and in vivo. [Tissue Eng Part A] Abstract Epigenetic Regulation of Myofibroblast Differentiation and Extracellular Matrix Production in Nasal Polyp-Derived Fibroblasts Researchers aim was to study the effect of trichostatin A on transforming growth factor-β1-induced myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts. [Clin Exp Allergy] Abstract Growth Factor Regulation of Corneal Keratocyte Mechanical Phenotypes in Three-Dimensional Collagen Matrices The purpose of this study was to assess how wound healing cytokines and the extracellular matrix environment regulate the keratocyte mechanical phenotype. [Invest Ophthalmol Vis Sci] Abstract Passive and Active Contributions to Generated Force and Retraction in Heart Valve Tissue Engineering Within this study, researchers unraveled the passive and active contributions of cells and matrix to generated force and retraction in engineered heart valve tissues. [Biomech Model Mechanobiol] Abstract The Inhibition of Hyaluronan Degradation Reduced Pro-Inflammatory Cytokines in Mouse Synovial Fibroblasts Subjected to Collagen-Induced Arthritis Researchers aimed to investigate the effects of inhibiting hyaluronan degradation on synovial fibroblasts obtained from normal DBA/J1 mice and on synovial fibroblasts obtained from mice subjected to collagen induced arthritis, both fibroblast types stimulated with tumor necrosis factor-α. [J Cell Biochem] Abstract Extracellular Acidosis Accelerates Bone Resorption by Enhancing Osteoclast Survival, Adhesion, and Migration Researchers’ findings indicate that extracellular acidosis stimulates bone resorption by extending osteoclast survival and facilitating osteoclast adhesion and migration. [Biochem Biophys Res Commun] Abstract |